影像学技术评估慢性骨髓炎感染范围的研究进展 |
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Received:September 23, 2024
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作者 | Author | 单位 | Unit | E-Mail |
史卫东 |
SHI Wei-dong |
中国人民解放军总医院第四医学中心, 北京 100084 |
The Fourth Medical Center of Chinese PLA General Hospital, Beijing 100084, China |
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韩文兴 |
HAN Wen-xing |
中国人民解放军总医院第四医学中心, 北京 100084 |
The Fourth Medical Center of Chinese PLA General Hospital, Beijing 100084, China |
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张建政 |
ZHANG Jian-zheng |
中国人民解放军总医院第四医学中心, 北京 100084 |
The Fourth Medical Center of Chinese PLA General Hospital, Beijing 100084, China |
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张熔基 |
ZHANG Rong-ji |
中国人民解放军总医院第四医学中心, 北京 100084 |
The Fourth Medical Center of Chinese PLA General Hospital, Beijing 100084, China |
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何红英 |
HE Hong-ying |
中国人民解放军总医院第四医学中心, 北京 100084 |
The Fourth Medical Center of Chinese PLA General Hospital, Beijing 100084, China |
doctorhehongying@163.com |
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期刊信息:《中国骨伤》2025年38卷,第3期,第314-318页 |
DOI:10.12200/j.issn.1003-0034.20240445 |
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慢性骨髓炎清创不彻底是导致复发的主要因素。在治疗慢性骨髓炎时,彻底清除感染源是防止复发的关键。这一过程不仅包括全面清除感染灶、死骨、增生的瘢痕组织和肉芽组织,还包括消除死腔和改善局部血液循环。在这些步骤中,清创是一项核心程序,判断清创范围又是能否彻底清创的前提。本文系统回顾了不同影像学技术在评估慢性骨髓炎感染范围中的应用,并探讨了其未来发展趋势。传统X线平片虽然能初步提示骨髓炎,但难以明确感染范围;CT扫描具有精确的解剖定位功能,对于术前评估骨感染范围有重要的意义,但对软组织信息识别有限;MRI则以其高敏感性清晰区分感染骨与软组织,对软组织感染的评估有重要的提示作用,但可能高估骨感染范围。核素技术如18F-FDG PET/CT和SPECT/CT在术前精准评估感染范围上展现出巨大潜力。未来,通过优化不同影像学技术的组合应用,结合临床症状、术中情况与病理结果,并开发基于人工智能的影像分析平台,将能更精准地评估感染范围,为慢性骨髓炎患者提供更为有效、个性化的治疗方案,提升治疗效果,显著改善患者的生活质量。 |
[关键词]:影像学技术 慢性骨髓炎 估计值 感染范围 综述 |
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Progress on imaging techniques to assessent of the extent of chronic osteomyelitis |
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Abstract:Incomplete debridement of chronic osteomyelitis is the main factor leading to recurrence. For the treatment of chronic osteomyelitis,the complete elimination of the source of infection is the key to preventing recurrence. This process includes not only the complete removal of infected lesions,dead bone,accreted scar tissue and granulation tissue,but also the elimination of dead space and improved local blood circulation. In these steps,debridement is a core procedure,and judging the scope of debridement is the premise of whether it could be completely debridement. This article systematically reviewed the application of different imaging techniques in evaluating the scope of chronic osteomyelitis infection,and discusses its future development trend. Although traditional plain X-ray film could preliminarily indicate osteomyelitis,it is difficult to determine the infection scope. CT scan has the function of accurate anatomic localization,which is important for preoperative assessment of the scope of bone infection,but the recognition of soft tissue information is limited. MRI,with its high sensitivity,clearly distinguishes between infected bone and soft tissue,which plays an important role in the evaluation of soft tissue infection,but may overestimate the extent of bone infection. Nuclide techniques such as 18F-FDG PET/CT and SPECT/CT show great potential for accurately assessing the extent of infection before surgery. In the future,by optimizing the combination of different imaging technologies,combining clinical symptoms,intraoperative conditions and pathological results,and developing an image analysis platform based on artificial intelligence,it will be able to more accurately assess the scope of infection,provide more effective and personalized treatment plans for patients with chronic osteomyelitis,enhance treatment effects,and significantly improve quality of life of patients. |
KEYWORDS:Imaging technology Chronic osteomyelitis Estimate Infection range Review |
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引用本文,请按以下格式著录参考文献: |
中文格式: | 史卫东,韩文兴,张建政,张熔基,何红英.影像学技术评估慢性骨髓炎感染范围的研究进展[J].中国骨伤,2025,38(3):314~318 |
英文格式: | SHI Wei-dong,HAN Wen-xing,ZHANG Jian-zheng,ZHANG Rong-ji,HE Hong-ying.Progress on imaging techniques to assessent of the extent of chronic osteomyelitis[J].zhongguo gu shang / China J Orthop Trauma ,2025,38(3):314~318 |
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