| 非创伤性股骨头坏死与血浆脂蛋白的相关性研究 |
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投稿时间：2002-09-04
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| 作者 | Author | 单位 | Address | E-Mail |
| 陈卫衡 |
CHEN Weiheng |
中国中医研究院骨伤科研究所,北京100700 |
Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700 |
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| 林娜 |
LIN Na |
中国中医研究院中药研究所 |
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| 郭效东 |
GUO Xiaodong |
中国中医研究院骨伤科研究所,北京100700 |
Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700 |
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| 张洪美 |
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中国中医研究院骨伤科研究所,北京100700 |
Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700 |
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| 孙钢 |
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中国中医研究院骨伤科研究所,北京100700 |
Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700 |
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| 张磊 |
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中国中医研究院骨伤科研究所,北京100700 |
Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700 |
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| 顾力军 |
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中国中医研究院骨伤科研究所,北京100700 |
Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700 |
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| 赵铁军 |
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中国中医研究院骨伤科研究所,北京100700 |
Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700 |
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| 期刊信息：《中国骨伤》2003年，第16卷，第2期，第69-70页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目: |
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中文摘要:
目的：研究非创伤性股骨头坏死与血浆脂质变化的相关性。
方法：研究对象120例,其中60例非创伤性股骨头坏死患者和60例正常人,采用奥林帕斯(Olypas)AU400全自动生化分析仪,检测总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、载脂蛋白AI(ApoAI)、载脂蛋白B(ApoB)等指标。
结果:股骨头坏死组与正常对照组血浆脂质及载脂蛋水平比较,TC、TG、LDL、ApoB明显升高(P<0.05),HDL、ApoAI明显降低(P<0.05),ApoB/ApoAI比值显著升高(P<0.001).
结论：非创伤性股骨头坏死的发生和发展与血浆中的脂蛋白有密切关系,ApoB/ApoAI比值升高对估计非创伤性骨坏死的发生具有一定的临床意义。 |
| 【关键词】股骨头坏死 载脂蛋白B 载脂蛋白AI |
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| A study on the relationship between plasma lipoprotein and non-traumatic necrosis of the femoral head |
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ABSTRACT
Objective:To study the relationship between non-traumatic necrosis of the femoral head and blood plasma lipid
Methods:60 patients and 60 normal people were included in the study.Total cholesterol(TC),triglyceride(TG),high density lipoprotein(HDL),low density lipoprotein(LDL),apolipoprotein AI(ApoAI)and apolipoprotein B(ApoB) were determined with the automatism biochemical analysor of Olypas AU 400.
Results:Comparison between the patients and the normal controls showed that TC,TG,LDL and ApoB were significantly higher,(P<0.05),HDL and ApoAI were significantly lower in the patients than that in the normal control(P<0.05).ApoB/ApoAI ratio was also significantly higher in the patients than that in the normal control (P<0.001).
Conclusion:There was a significant association between change of lipoprotein and development of non-traumatic necrosis of the femoral head.A high ApoB/ApoAI ratio has clinical significance to estimate developing of non-traumatic osteonecrosis. |
| KEY WORDS Femur head necrosis Apo B Apo AI |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 陈卫衡,林娜,郭效东,张洪美,孙钢,张磊,顾力军,赵铁军.非创伤性股骨头坏死与血浆脂蛋白的相关性研究[J].中国骨伤,2003,16(2):69~70 |
| 英文格式: | CHEN Weiheng,LIN Na,GUO Xiaodong.A study on the relationship between plasma lipoprotein and non-traumatic necrosis of the femoral head[J].zhongguo gu shang / China J Orthop Trauma ,2003,16(2):69~70 |
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