盘内注射胶原酶治疗上段腰椎间盘突出症
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作者Author单位AddressE-Mail
燕春山 YAN Chun-shan 解放军第404医院风湿科,山东威海264200 Rheumatism Department of the 404th Hospital of PLA,Weihai 264200,Shandong,China  
从凤英 CONG Feng-ying 济南军区总院  
刘玉波 LIU Yu-bo 解放军第404医院风湿科,山东威海264200 Rheumatism Department of the 404th Hospital of PLA,Weihai 264200,Shandong,China  
刘晓光 LIU Xiao-guang 解放军第404医院风湿科,山东威海264200 Rheumatism Department of the 404th Hospital of PLA,Weihai 264200,Shandong,China  
郑晓红 ZHENG Xiao-hong 解放军第404医院风湿科,山东威海264200 Rheumatism Department of the 404th Hospital of PLA,Weihai 264200,Shandong,China  
期刊信息:《中国骨伤》2007年,第20卷,第11期,第767-768页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz
基金项目:
中文摘要:

目的:探讨盘内注射胶原酶的方法治疗上段腰椎间盘突出症的可行性、疗效及安全性。

方法:28例单纯上段腰椎间盘突出症患者,男16例,女12例;年龄21~62岁,平均44.5岁。病程3个月~10年。椎间盘突出4~9mm,平均4.9mm。采用椎旁进针盘内注射或突出物内注射胶原酶的方法进行治疗,随访观察有效率、突出椎间盘溶解、椎间隙感染等并发症发生情况。

结果:所有患者随访1~6个月,依据Macnab评价标准进行疗效评价,优9例,良12例,可4例,无效3例。突出椎间盘溶解0~6mm,平均3.5mm。17例进行了重复注射,其中9例患者进行了3次注射。13例注射后短期内症状加重,对症处理后缓解。

结论:盘内注射胶原酶的方法治疗上段腰椎间盘突出症效果理想、安全可行。
【关键词】胶原酶类  椎间盘化学松解术  椎间盘移位  腰椎
 
Collagenase injected in disk to treat lumbar intervertebral disk herniation
ABSTRACT  

Objective:To probe the therapeutic effect in the treatment of up intervertebral disc herniation by injected collagenase in disk.

Methods:There were 28 patients involving 16 males and 12 females with an average age of 44.5 years ranging from 21 to 62.The course was 3 months to 10 years.The average disc herniation was 4.9 mm ranging from 4 to 9 mm.The lumbar disc herniation were treated by collagenase injected in disk.The outcome,solution of herniated disc,complications such as infection in disc were followed and observed.

Results:All patients were followed-up for 1 to 6 months.According to evaluated standard of Macnab,the result was excellent in 9 cases,good in 12,improved in 4,and ineffective in 3.The solution of herniated disk was 0-6 mm,the average was 3.5 mm.Seventeen patients were injected twice,of which 9 patients were injected three times.There were 13 cases with symptom progression after injection herniation is short period,but the situation was relieved after therapy in time.

Conclusion:The effect of injection of collagenase in disk to treat lumber intervertebral disk herniation is an effective and safe method.
 
引用本文,请按以下格式著录参考文献:
中文格式:燕春山,从凤英,刘玉波,刘晓光,郑晓红.盘内注射胶原酶治疗上段腰椎间盘突出症[J].中国骨伤,2007,20(11):767~768
英文格式:YAN Chun-shan,CONG Feng-ying,LIU Yu-bo,LIU Xiao-guang,ZHENG Xiao-hong.Collagenase injected in disk to treat lumbar intervertebral disk herniation[J].zhongguo gu shang / China J Orthop Trauma ,2007,20(11):767~768
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