| Genex椎体成形在胸腰椎爆裂性骨折治疗中的意义 |
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投稿时间：2010-07-06
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| 期刊信息：《中国骨伤》2011年，第24卷，第3期，第223-226页 |
| DOI：10.3969/j.issn.1003-0034.2011.03.014 |
| 基金项目: |
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中文摘要:
目的：探讨Genex椎体成形与椎弓根钉系统复位固定胸腰椎爆裂性骨折的方法与疗效。
方法：自2007年2月至2009年10月，应用Genex人工骨椎体成形与椎弓根钉系统复位固定胸腰椎爆裂性骨折38例，其中男25例，女13例；平均年龄42岁(30～68岁).致伤原因：车祸伤9例，压砸伤7例，坠落伤21例，其他伤1例。骨折类型按Denis分类：A型6例，B型22例，C型7例，D型3例。神经功能损害按(ASIA)标准分级：A级4例，B级7例，C级10例，D级6例，E级11例。术后通过X线片、CT检查以及(ASIA)神经功能评定标准评价手术疗效。
结果：38例均获随访，时间6～34个月，平均16.5个月。术后1周X线检查：脊柱序列恢复正常，术后椎体前缘高度恢复(98.50±2.17)%,椎体后缘高度恢复(98.87±1.82)%,Cobb角降(1.63±2.15)°，椎管狭窄率恢复(1.45±3.47)%.术后6个月X线片显示椎体高度、Cobb角恢复无丢失，椎体骨组织密度接近正常。CT扫描发现椎体内骨缺损完全消失，骨缺损区已为正常骨组织。术后神经功能均有1～2级的恢复。
结论：Genex人工骨作为植骨材料进行椎体成形术，生物相容性好，骨诱导能力强，椎体高度及Cobb角丢失少，近期效果满意。 |
| 【关键词】胸椎 腰椎 骨折 骨折固定术 骨移植 |
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| Significance of percutaneous vertebroplasty with Genex in the treatment of thoracolumbar burst fractures |
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ABSTRACT
Objective: To explore the therapeutic effects of percutaneous vertebroplasty with Genex combined with pedical screw fixation in the treatment of thoracolumbar burst fractures.
Methods: From February 2007 to October 2009,38 patients with thoracolumbar burst fractures were treated with percutaneous vertebroplasty with Genex and pedical screw fixation. There were 25 males and 13 females,with a mean age of 42 years old(ranged,30 to 68 years). The cause of injuries included road accident of 9 cases,crush injury of 7 cases,crash of 21 cases and others of 1 case. The fractures were classified according to Denis classification:6 cases of type A,22 cases of type B,7 cases of type C and 3 cases of type D. Functional assessment of nerves was assesed according to ASIA criteria:4 cases of type A,7 cases of type B,10 cases of type C,6 cases of type D and 11 cases of type E. Therapeutic effects were assessed by imaging and ASIA standard.
Results: All the patients were followed up,and the duration ranged from 6 months to 34 months,with a mean period of 16.5 months. The results were observed after 1 week by X-ray inspection that vertebrate column array of all patients were restored to normal,anterior height of centrum restored to (98.50±2.17)%,posterior height of centrum for (98.87±1.82)%;and Cobb angle of injured vertebra decreased to average of(1.63±2.15) degree;the stenosis rate restored to(1.45±3.47)%. By X-ray inspection,it was observed that the vertebral height kept good at 6 months after operation,and the bone density almostly normal. By CT scanning,it was observed that bone defects of vertebrae disappeared,and restored to normal bony tissue. The nerve function restored 1 to 2 grades 6 months after operation.
Conclusion: Artificial bone of Genex applied in vertebral body-plasty has good biocompatibility,strong bone inducibility,no complications,little loss of vertebrae height and Cobb angle,and satisfactory results in the near future. |
| KEY WORDS Thoracic vertebrae Lumbar vertebrae Fractures Fracture fixation Bone transplantation |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 占蓓蕾,叶舟.Genex椎体成形在胸腰椎爆裂性骨折治疗中的意义[J].中国骨伤,2011,24(3):223~226 |
| 英文格式: | ZHAN Bei-lei,YE Zhou.Significance of percutaneous vertebroplasty with Genex in the treatment of thoracolumbar burst fractures[J].zhongguo gu shang / China J Orthop Trauma ,2011,24(3):223~226 |
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