| 塌陷前期股骨头坏死的保头手术治疗的进展 |
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投稿时间：2016-09-20
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| 作者 | Author | 单位 | Address | E-Mail |
| 叶奕亨 |
YE Yi-heng |
温州医科大学附属第一医院新院区, 浙江 温州 325000 |
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China |
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| 陈凯 |
CHEN Kai |
温州医科大学附属第一医院新院区, 浙江 温州 325000 |
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China |
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| 金可可 |
JIN Ke-ke |
温州医科大学附属第一医院新院区, 浙江 温州 325000 |
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China |
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| 张一帆 |
ZHANG Yi-fan |
温州医科大学附属第一医院新院区, 浙江 温州 325000 |
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China |
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| 陈雷 |
Chen Lei |
温州医科大学附属第一医院新院区, 浙江 温州 325000 |
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China |
chenlei689595@gmail.com |
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| 期刊信息：《中国骨伤》2017年，第30卷，第3期，第287-292页 |
| DOI：10.3969/j.issn.1003-0034.2017.03.021 |
| 基金项目: |
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| 中文摘要:股骨头坏死是一种由多种原因引起股骨头血运障碍而导致骨细胞及骨髓成分的死亡，最终导致股骨头塌陷，进而影响髋关节功能的难治性疾病。其治疗关键在于早期诊断并治疗，防止骨塌陷，延迟或避免髋关节置换手术。该病早期有很多外科手术治疗方法，至今仍无公认的确切有效的治疗方案。现主流以髓芯减压术为基础，联合骨移植术、钽棒植入术、骨髓间充质干细胞等方案治疗股骨头坏死。另外也有数种截骨术通过改变负重部位以减轻压力，延缓股骨头坏死。其中钽棒由于优缺点众多，其对股骨头坏死的治疗作用仍有争议，而骨髓间充质干细胞移植法治疗早期股骨头坏死展现出了巨大潜力。 |
| 【关键词】股骨头坏死 保头手术治疗 骨髓 间质干细胞移植 综述 |
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| Progress on surgical treatment for femoral head-preservering in the precollapse stage of femoral head necrosis |
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| ABSTRACT Osteonecrosis of the femoral head(ONFH),a refractory disease characterized by death of the osteocytes and the bone marrow due to inadequate blood supply caused by various mechanisms,usually leads to the collapse of the femoral head and malfunction of the hip joint. The crux is to diagnose ONFH early in the precollapse stage and prevent subsequent progression of collapsing through early interventions,thus delaying or avoiding the replacement of the hip joint. A number of joint salvaging operation treatments for early stage ONFH are available. However,there has been no consensus with regard to the ideal treatment. The main trend now is to unite core decompression with bone-grafting,tantalum rod,bone marrow mesenchymal stem cell(BMSC)and other treatments. Also there are ways of osteotomy altering the angle of the femoral neck to relocate necrotic tissue from the weight-bearing segment. The implanting of tantalum rod remains controversial and the advent of bone marrow mesenchymal stem cell(BMSC)holds huge potential. |
| KEY WORDS Femur head necrosis Femoral head-preservering Bone marrow Mesenchymal stem cell transplantation Review |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 叶奕亨,陈凯,金可可,张一帆,陈雷.塌陷前期股骨头坏死的保头手术治疗的进展[J].中国骨伤,2017,30(3):287~292 |
| 英文格式: | YE Yi-heng,CHEN Kai,JIN Ke-ke,ZHANG Yi-fan,Chen Lei.Progress on surgical treatment for femoral head-preservering in the precollapse stage of femoral head necrosis[J].zhongguo gu shang / China J Orthop Trauma ,2017,30(3):287~292 |
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