| 糖预处理对髋关节置换手术患者快速康复外科效果的影响 |
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投稿时间：2019-12-14
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| 作者 | Author | 单位 | Address | E-Mail |
| 苗巍 |
MIAO Wei |
焦作煤业集团有限责任公司中央医院骨一科, 河南 焦作 454000 |
The First Department Orthopaedics, Central Hospital of Jiaozuo Coal Industry Co. LTD, Jiaozuo 454000, Henan, 454000, China |
MIAOWEI19780910@163.com |
| 张之智 |
ZHANG Zhi-zhi |
焦作煤业集团有限责任公司中央医院骨一科, 河南 焦作 454000 |
The First Department Orthopaedics, Central Hospital of Jiaozuo Coal Industry Co. LTD, Jiaozuo 454000, Henan, 454000, China |
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| 卢伟 |
LU Wei |
焦作煤业集团有限责任公司中央医院骨一科, 河南 焦作 454000 |
The First Department Orthopaedics, Central Hospital of Jiaozuo Coal Industry Co. LTD, Jiaozuo 454000, Henan, 454000, China |
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| 张鑫 |
and ZHANG Xin |
焦作煤业集团有限责任公司中央医院骨一科, 河南 焦作 454000 |
The First Department Orthopaedics, Central Hospital of Jiaozuo Coal Industry Co. LTD, Jiaozuo 454000, Henan, 454000, China |
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| 期刊信息：《中国骨伤》2020年，第33卷，第8期，第730-735页 |
| DOI：10.12200/j.issn.1003-0034.2020.08.009 |
| 基金项目: |
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中文摘要:目的：探究糖预处理在髋关节置换手术患者快速康复外科中的应用效果，为今后临床治疗提供参考。
方法：自2016年6月至2018年6月采用髋关节置换手术治疗168例患者，男100例，女68例；年龄25~90（52.05±5.73）岁，分为对照组和观察组，各84例。两组患者均采用快速康复外科理念治疗，对照组术前给予传统禁食水干预，观察组术前给予糖预处理。比较手术前后空腹血糖（fasting blood glucose，FBG），C肽，空腹胰岛素定量（fasting insulin，FINS）水平和血清免疫球蛋白G（IgG），免疫球蛋白M（IgM），免疫球蛋白A（IgA），总淋巴细胞计数（total lymphocyte count，TLC）水平，并比较术后口渴、恶心、疲劳、虚汗、胃部不适、焦虑、饥饿、头晕的不适感感受度。
结果：168例患者全部随访，术前观察组与对照组的FBG、C肽和FINS水平比较差异无统计学意义（P>0.05）；术后较术前FBG、C肽和FINS水平均升高，且观察组的C肽和FINS水平低于对照组（P<0.05）。术前观察组与对照组的血清IgG、IgM、IgA、TLC水平比较差异无统计学意义（P>0.05）；术后较术前血清IgG、IgM、IgA、TLC水平均升高，且观察组高于对照组（P<0.05）。术后观察组和对照组的口渴、恶心、疲劳、虚汗、胃部不适的不适感程度比较差异无统计学意义（P>0.05）；观察组术后焦虑、饥饿、头晕的不适感程度轻于对照组（P<0.05）。
结论：髋关节置换手术患者术前进行糖预处理可缓解胰岛素抵抗，提高免疫力，改变空腹下能量储存，可在临床中推广和使用。 |
| 【关键词】关节成形术,置换,髋 快速康复外科 禁食 禁水 糖预处理 |
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| Effect of glucose pretreatment on the effect of rapid rehabilitation surgery in patients undergoing hip replacement |
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ABSTRACT Objective: To explore the effect of glucose pretreatment in the rapid rehabilitation surgery of hip replacement patients,and to provide reference for the future clinical treatment.
Methods: From June 2016 to June 2018,168 patients (100 males,68 females) were treated with hip replacement. The patients were divided into control group and observation group,84 cases in each group,aged 25 to 90(52.05±5.73) years old. Both groups were treated with the concept of rapid rehabilitation surgery,the control group was given traditional fasting water deprivation before operation,and the observation group was given glucose pretreatment before operation. The levels of fasting blood glucose(FBG),C-peptide,fasting insulin(FINS),IgG,IgM,IgA and total lymphocyte count(TLC) were compared before and after operation,and the sensitivity of thirst,nausea,fatigue,sweating,stomach discomfort,anxiety,hunger and dizziness were compared.
Results: All the 168 patients were followed up. There was no significant difference in FBG,C-peptide and fins levels between the observation group and the control group(P>0.05). The levels of FBG,C-peptide and fins in the observation group were higher than those in the control group(P<0.05). There was no significant difference in the serum IgG,IgM,IgA and TLC levels between the observation group and the control group(P>0.05);the serum IgG,IgM,IgA and TLC levels after operation were higher than those before operation,and the observation group was higher than the control group(P<0.05). There was no significant difference in the degree of thirst,nausea,fatigue,sweating and stomach discomfort between the observation group and the control group(P>0.05);the degree of anxiety,hunger and dizziness in the observation group was less than that in the control group(P<0.05).
Conclusion: Glucose pretreatment before hip replacement can relieve insulin resistance,improve immunity and change energy storage under fasting,which can be widely used in clinic. |
| KEY WORDS Arthroplasty,replacement,hip Rapid rehabilitation surgery Fasting Water deprivation Glucose pretreatment |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 苗巍,张之智,卢伟,张鑫.糖预处理对髋关节置换手术患者快速康复外科效果的影响[J].中国骨伤,2020,33(8):730~735 |
| 英文格式: | MIAO Wei,ZHANG Zhi-zhi,LU Wei,and ZHANG Xin.Effect of glucose pretreatment on the effect of rapid rehabilitation surgery in patients undergoing hip replacement[J].zhongguo gu shang / China J Orthop Trauma ,2020,33(8):730~735 |
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