| 3D打印个性化腰椎融合器设计及生物力学性能研究分析 |
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投稿时间：2020-05-19
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| 作者 | Author | 单位 | Address | E-Mail |
| 任捷 |
REN Jie |
山西医科大学第二医院骨科, 山西 太原 030001 |
Department of Orthopaedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China |
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| 吕智 |
LYU Zhi |
山西医科大学第二医院骨科, 山西 太原 030001 |
Department of Orthopaedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China |
1191866858@qq.com |
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| 期刊信息：《中国骨伤》2021年，第34卷，第8期，第764-769页 |
| DOI：10.12200/j.issn.1003-0034.2021.08.014 |
| 基金项目: |
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中文摘要:
目的：利用有限元分析方法比较个体化整体型融合器、临床标准双枚子弹头型融合器和健康腰椎在不同工况下腰椎模型生物力学性能的差异。
方法：根据真实健康人体腰椎CT扫描数据，利用有限元软件设计出健康人体腰椎的有限元模型作为正常对照组。以此为基础进一步建立个体化整体型融合器腰椎模型和临床标准双枚子弹头型融合器腰椎模型。对3种有限元模型分别施加垂直压缩、前屈、后伸、侧弯等不同载荷，观察腰椎各部件的应力分布与应力大小的变化。
结果：临床标准双枚子弹头型融合器腰椎模型中椎体与融合器在后伸工况下受到的应力值最大，分别为45.81 MPa和97.07 MPa。个体化整体型腰椎模型中椎体与融合器的受力更接近健康腰椎模型中椎体与椎间盘的受力。从位移的角度来看，两种融合器腰椎模型各部件的位移均小于健康腰椎模型，说明融合器内固定限制了椎体的活动范围，侧面印证了研究中所建立有限元模型的有效性。而不同工况下个体化整体型融合器腰椎模型中融合器和椎体的位移普遍要比临床标准双枚子弹头型融合器腰椎模型融合器和椎体位移小。
结论：融合器在某种程度上能够很好的代替病变的椎间盘，从而达到减少患者疼痛恢复腰椎功能的目的；而融合器的个性化设计则更能满足个体患者的需求，并且对患者腰椎功能的恢复、融合器的使用寿命和相接触椎体的保护都有重要意义，为实际的临床治疗提供了一定的指导。 |
| 【关键词】脊柱融合术 打印,三维 人工植入物 有限元分析 |
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| 3D printed personalized lumbar spinal fusion device design and biomechanical performance analysis |
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ABSTRACT
Objective: The finite element analysis method was used to compare the biomechanical performance of the individualized interbody fusion cage,the clinically common double bullet type fusion cage and the healthy lumbar spine model under different working conditions.
Methods: According to the CT scan data of the lumbar spine of a real healthy human body,a finite element model of the lumbar spine of a healthy human body was designed using finite element software as a normal control group. On this basis,the individualized lumbar fusion cage model and the clinical standard bullet-type fusion cage lumbar spine model were further established. These three finite element models were applied with different loads such as vertical compression,forward flexion,extension,and lateral bending to observe the changes in the stress distribution and stress magnitude of each component of the lumbar spine.
Results: The maximum stress values of the vertebral body and the fusion cage under the extension condition in the clinical standard bullet-type fusion cage lumbar spine model were 45.81 MPa and 97.07 MPa,respectively. The stress of the vertebral body and the fusion cage in the individualized lumbar fusion cage model was closer to the stress of the vertebral body and the intervertebral disc in the healthy lumbar spine model. From the perspective of displacement,the displacement of each component of the lumbar spine models of the two fusion cages was smaller than that of the healthy lumbar spine model,indicated that the internal fixation of the fusion cage limited the range of motion of the vertebral body. On the other hand,it also confirmed the validity of the finite element model established in the study. The displacement of the fusion cage and the vertebral body in the individualized model under different working conditions was generally smaller than that of the standard model fusion cage and the vertebral body.
Conclusion: The fusion cage can replace the diseased intervertebral disc to a certain extent,so as to reduce the patient's pain and restore the lumbar function. The personalized design of the fusion cage can better meet the needs of individual patients,which has the great significance to the recovery of the patient's lumbar spine function,the service life of the fusion cage and the protection of the contact vertebral body,and provides certain guidance for actual clinical treatment. |
| KEY WORDS Spinal fusion Printing,three-dimensional Artificial implants Finite element analysis |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 任捷,吕智.3D打印个性化腰椎融合器设计及生物力学性能研究分析[J].中国骨伤,2021,34(8):764~769 |
| 英文格式: | REN Jie,LYU Zhi.3D printed personalized lumbar spinal fusion device design and biomechanical performance analysis[J].zhongguo gu shang / China J Orthop Trauma ,2021,34(8):764~769 |
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