经皮椎体强化术围手术期隐性失血的相关因素分析
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作者Author单位AddressE-Mail
吴智华 WU Zhi-hua 广州中医药大学第一临床医学院, 广东 广州 510405  
莫凌 MO Ling 广州中医药大学第一临床医学院, 广东 广州 510405
广州中医药大学第三附属医院脊柱骨科, 广东 广州 510240
 
程浣彤 CHENG Huan-tong 广州中医药大学第一临床医学院, 广东 广州 510405  
梁德 LIANG De 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 Department of Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
崔健超 CUI Jian-chao 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 Department of Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
唐晶晶 TANG Jing-jing 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 Department of Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
任辉 REN Hui 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 Department of Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
姚珍松 YAO Zhen-song 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 Department of Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
江晓兵 JIANG Xiao-bing 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 Department of Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China spinedrjxb@sina.com 
期刊信息:《中国骨伤》2022年,第35卷,第8期,第732-735页
DOI:10.12200/j.issn.1003-0034.2022.08.006
基金项目:国家自然科学基金(编号:81774338)
中文摘要:

目的:探讨经皮椎体强化术治疗骨质疏松性椎体压缩骨折患者围手术期隐性失血的影响因素。

方法:回顾性分析2018年10月至2019年12月行经皮椎体强化术的360例患者的临床资料,包括性别,年龄,手术方式,病程,身高,体重,手术节段,骨密度,骨水泥量,手术时间,椎体高度丢失率,椎体高度恢复率,骨水泥渗漏,凝血功能,术前及术后血红蛋白(hemoglobin,Hb),红细胞比容(hematocrit,HCT)和内科合并症等。根据Gross公式计算总失血量,采用t检验、多元线性回归和单因素方差分析不同因素对隐性失血的影响。

结果:手术方式、手术节段、病程、骨水泥渗漏、术前Hb、椎基底静脉型渗漏和椎体节段静脉型渗漏与隐性失血显著相关(P<0.05)。

结论:经皮椎体后凸成形术、双节段及多节段手术、病程≥ 6周、骨水泥椎基底静脉型渗漏和椎体节段静脉型渗漏,以及术前Hb越低的患者围手术期隐性失血越多。
【关键词】骨质疏松  脊柱骨折  经皮椎体强化术  隐性失血  相关因素分析
 
Risk factors of hidden blood loss in percutaneous vertebral augmentation
ABSTRACT  

Objective: To explore the risk factors of hidden blood loss in osteoporosis vertebral compression fractures during percutaneous vertebral augmentation.

Methods: From October 2018 to December 2019, 360 patients with osteoporosis vertebral compression fractures who received percutaneous vertebral augmentation were enrolled in this study. The factors analyzed included gender, age, surgical methods, disease course, height, weight, the operative segment, bone mineral density, amount of bone cement, operative time, percentage of height loss, percentage of vertebral height restoration, cement leakage, blood clotting function, preoperative and postoperative hemoglobin and hematocrit and other internal diseases. Total blood loss was calculated by Gross's formula, influential factors of the hidden blood loss were further analyzed by t-test, multivariate linear regression and one-way ANOVA analysis.

Results: Surgical methods, the operative segment, disease course, cement leakage, preoperative hemoglobin, cement leakage via the basivertebral and segmental vein were significantly correlated with hidden blood loss(P<0.05).

Conclusion: Patients with percutaneous kyphoplasty, two-level and multi-level surgery, the course of the disease beyond 6 weeks, cement leakage via the basivertebral and segmental vein, and lower preoperative hemoglobin had more perioperative hidden blood loss.
KEY WORDS  Osteoporosis  Spinal fractures  Percutaneous vertebral augmentation  Hidden blood loss  Relative factors analysis
 
引用本文,请按以下格式著录参考文献:
中文格式:吴智华,莫凌,程浣彤,梁德,崔健超,唐晶晶,任辉,姚珍松,江晓兵.经皮椎体强化术围手术期隐性失血的相关因素分析[J].中国骨伤,2022,35(8):732~735
英文格式:WU Zhi-hua,MO Ling,CHENG Huan-tong,LIANG De,CUI Jian-chao,TANG Jing-jing,REN Hui,YAO Zhen-song,JIANG Xiao-bing.Risk factors of hidden blood loss in percutaneous vertebral augmentation[J].zhongguo gu shang / China J Orthop Trauma ,2022,35(8):732~735
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