| 应用神经延长架延长兔坐骨神经的实验研究 |
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摘要点击次数: 1773
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投稿时间：2002-01-30
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| 期刊信息：《中国骨伤》2003年，第16卷，第2期，第87-90页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目: |
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中文摘要:
目的：利用神经延长器延长周围神经,修复周围神经缺损,为临床应用提供依据。
方法：利用自制的神经延长架,每天分数次延长1mm,修复神经缺损10mm,9周后行电生理及组织学观察。
结果:延长段神经外膜血供基本正常,神经缺损修复后其神经刺激阈值与神经原位缝合组差异无显著性,与神经移植组差异有显著性,组织学观察,延长组和原位缝合组有基本正常组织结构,神经移植组有明显空泡变性,髓鞘凝固变性。
结论：应用神经延长装置,采用合适的连接方法,可有效的延长周围神经,修复神经缺损。 |
| 【关键词】周围神经 神经移植 神经外科手术 |
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| An experimental study of rabbits sciatic nerve distracting lengthening with nerve lengthening device for repair of peripheral nerve injury |
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ABSTRACT
Objective:Using a nerve lengthening apparatus to distract nerve for repair of peripheral nerve injury and to provide a basis for clinical application
Methods:30 health domestic rabbits were divided into 4 groups.Group A,the injuried nerve was distracted;Group B,nerve was transpanted in primary position;Group C,anastomosis had been performed in between the cut nerve endings in primary position;Group D,branch of sciatic nerve was cut down.After 9 weeks of operation,electron physiological examination,histology observation and nerve fibre count were performed.
Results:Perineurium blood supply of lengthened nerve segment was almost normal.After repair of the injured nerve,the stimulation threshold value,showed no difference between Group A and Group B (P>0.05),but there was a difference between Group A and Group D (P<0.05),and there was a significant difference between Group A and Group C (P<0.01).Under optic microscope and electron microscope,it was found that there was an almost normal structure in Group A and Group C and there was a significant vacuole degeneration and myelin sheath coagulation degeneration.
Conclusion:Using nerve lengthening apparatus and suitable method of approximation,effective sciatic nerve lengthening can be done.After anastomosis,the injured nerve can be repaired.This study provides a new method of repairing nerve injury. |
| KEY WORDS Peripheral nerves Nerve transfer Neurosurgery |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 金帅星,朴虎林,石伟,朴华益,张志刚,金成峰.应用神经延长架延长兔坐骨神经的实验研究[J].中国骨伤,2003,16(2):87~90 |
| 英文格式: | JIN Shuaixing,PIAO Hulin,SHI Wei.An experimental study of rabbits sciatic nerve distracting lengthening with nerve lengthening device for repair of peripheral nerve injury[J].zhongguo gu shang / China J Orthop Trauma ,2003,16(2):87~90 |
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